Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic
Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic

4.9 star ratings

Syn-01 - New Generation of Synbiotic: Phage-first Synbiotic

The next generation of gut care starts with what most probiotics never had - bacteriophage technology.
PreforPro® phage prebiotic clears the path in hours. DE111® spore probiotics arrive intact and thrive where standard strains dissolve. Two mechanisms. One daily capsule. Zero fiber. Zero fermentation.

+2× BENEFICIAL BACTERIA GROWTH

DE111® clinically shown to increase Bifidobacterium levels vs placebo.

24-HOUR FAST-ACTING PHAGE

PreforPro® begins supporting microbial balance within the first day.

0% FIBER GAS TRADE-OFF

No inulin. No chicory. No fermentation-driven bloat.

100% ACID-RESISTANT BACILLUS SPORES

Naturally hardy Bacillus spores survive stomach acid intact - where standard strains dissolve.
Choose your option
$45.00
Estimate delivery between Jul 24 - Jul 27

ingredients

PreforPro®: A clinically studied, micro-dosed bacteriophage that selectively targets and reduces unwanted bacteria.

DE111® Spores: Armored Bacillus subtilis strains naturally equipped to survive stomach acid and bloom in the lower gut.

100% Fiber-Free: Zero inulin, zero bulky fibers, and zero gas-causing agents.

Other Ingredients: Non-GMO Vegetable Cellulose (Delayed-release capsule). Vegan, Gluten-Free, and Non-GMO Project Verified.

how to use it

Take two capsules daily.

May be taken with or without food.

For best results, take consistently at the same time each day to maintain a balanced microbiome environment.

Capsules can be opened and the contents mixed directly with water or juice if preferred.

warning

For adult use only. Not intended for children.

If you are pregnant, nursing, taking medications, or have a known medical condition, consult your healthcare professional before using this or any dietary supplement.

Keep out of reach of children. Do not use if the safety seal is broken or missing.

storage and expiration

No Refrigeration Required: Our spore-forming strains are naturally shelf-stable, making SYN-01 perfect for travel.

Store in a cool, dry place away from direct sunlight and moisture.

Guaranteed potency up to the expiration date printed on the bottom of the bottle when stored under recommended conditions.

advanced gut health starts here.

Trust the evolution of microbiome care with our science-backed, clinical-grade synbiotic.

FDA-Notified GRAS

Formulated with globally recognized, premium ingredients for your absolute peace of mind.

30+ Clinical Studies

DE111® is backed by extensive safety and efficacy research in human clinical trials.

100%

Acid Survivability. Standard probiotics die in harsh stomach acid. 

SYN-01’s spore-forming armor guarantees intact delivery to your lower gut, right where it matters most.

GMP Certified

Proudly manufactured in a state-of-the-art, certified facility to the highest quality standards.

100% Fiber-Free

No bulky fibers or hidden inulin. Zero gas, zero bloating—just predictable comfort.

Discover A New Era of Prebiotics.

Say goodbye to outdated, gas-causing fibers. PreforPro® is a clinically studied prebiotic that utilizes advanced phage technology to actively displace unwanted bacteria in the gut. Think of it as a precision "Weeder" that selectively clears out the bad strains, creating the perfect environment for healthy flora to thrive.

Learn more about PreforPro® at: Discover a Better Prebiotic with PreforPro®

clinically proven to reshape your gut microbiome.

*In human clinical trials, DE111® actively crowded out pathogens while multiplying beneficial flora. 

* Parameters measured: Average colony-forming units (ACFU) after administration. 

Boosts Good Bacteria

Reduces Bad Bacteria

What Should You Expect From Consistent Use of SYN-01?

HOURS 2 - 24

Rapid Relief: The "Weeder" takes action

PreforPro® begins targeting and eliminating harmful bacteria almost immediately. You may notice a fast reduction in gas, bloating, and post-meal discomfort.

WEEKS 2 - 4

Predictable Digestion: The "Seeder" takes root

DE111® spores establish themselves, multiplying beneficial flora. Your digestion becomes remarkably consistent, bowel movements are smooth, and the heavy, sluggish feeling after eating fades away.

MONTH 2 & BEYOND

Total Microbiome Reset: Systemic Balance

A balanced gut means a healthier you. You’ll experience sustained, clear energy, fortified immune support, and the ultimate confidence of a digestive system functioning at its absolute peak.

The Evolution of Gut Care 

Why cramming 50 Billion CFUs into a capsule doesn't mean better results. 

SYN-01

Advanced Phage + Spore Synbiotic

Protected Spores

Targets Pathogens First

100% Fiber-Free

Works in Hours

Precision Microbiome Reset

Standard Probiotics 

Generic High-CFU Formulas

Fragile Strains Die in Acid 

Blindly Adding Bacteria

Gas-Causing Fibers 

Takes Days or Weeks

Outdated Technology

real results. real relief.

Join the thousands who have reclaimed their digestive health and daily confidence with SYN-01’s precision synbiotic.

Got Questions?

Frequently Asked Questions

Why only 4.4 billion CFU?

CFU on the label doesn't tell you what reaches your gut. Most probiotic strains die in stomach acid before they ever get to work. SYN-01 uses spore-forming probiotics (DE111® and Bacillus coagulans) that are naturally acid-resistant - plus a delayed-release capsule to protect the other strains.

The result: more functional bacteria where they matter, not more on the label.

Is SYN-01 a "pure spore probiotic"?

SYN-01 is a hybrid synbiotic. Two of our four strains are spore-forming - DE111® (Bacillus subtilis) and Bacillus coagulans — for natural acid resistance. The other two: Lactobacillus acidophilus and Bifidobacterium lactis - are traditional strains protected by our delayed-release capsule.

This combination gives you the survival benefits of spores plus the strain diversity of clinically-studied traditional probiotics. The best of both approaches in one formula.

Is bacteriophage technology safe?

Bacteriophages have been studied since 1917. They're host-specific - targeting only certain bacteria, never affecting human cells or beneficial gut flora. PreforPro® is recognized as Generally Recognized as Safe (GRAS) by the FDA. You likely consume phages every day in fermented foods like yogurt, kimchi, and sauerkraut.

How long until I notice a difference?

Many customers report less afternoon bloating within the first 7-10 days. Spore probiotics typically establish their effect over 2-4 weeks of consistent use. For full microbial balance benefits, we recommend a minimum of 60 days. That's why we offer a 60-day money-back guarantee, your gut needs time to recalibrate, and we're confident it will.